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KMID : 0670719970020010029
Journal of the Korean Society Hyperthermia Oncology
1997 Volume.2 No. 1 p.29 ~ p.37
Development of Hyperthermia Engineering on the 21st Century in Korea
Sung Sil Chu
Abstract
Introduction
Hyperthermia is one of strong methods to treat cancer as like radiation, chemo-drugs
and surgery, and developed many kind of devices for heating, and applied clinical
medicine.
Research involving hyperthermia used simple heating methods such as water bath
immersion, microwave irradiation from a single waveguide aperture applicator, or
radiofrequency electrodes. Treatment monitoring consisted of measuring temperatures at
a few points within the treatment field.
Advances are occurring in methods of heating. It is now possible to deposit energy
effectively at depth. Efforts are underway to understand and predict the power
deposition patterns and resultant temperature distribution so that therapy can proceed
safely and with confidence. Treatment monitoring is understood to imply recording
temperatures and temperature transients at many points with the side of computerized
data acquisition systems.
Numerical programs are being developed that can assist in comparing the
characteristics of various devices, predict SAR (specific absorption rate) distributions in
realistic circumstances, and guide instrumentation developments. Thermal dosimetry now
implies extensive thermal modeling. While 3-dimensional programs suitable for detailed
treatment planning and retrospective dose calculations are not yet available.
Dr. Hall stated that, in the field of hyperthermia, "Although the biology is clearly on
our side, the picture is considerably different for the physics of localized hyperthermia,
the basic principles of which appear to be against us." The situation is changing as
more specialists from a number of disciplines begin applying their skills to this field.
Developments in heating technology for 21st century are discussed in terms of regional
heating, focal heating and whole body techniques. Thermometry system and treatment
monitoring are described as it relates to calibration standards, types of probes and
measurements needed in the clinic, and the nature of the data acquisition systems.
Thermal dosimetry is the calculational aspect of determining temperature distributions,
relating these to measured temperatures at specific points, and determining the thermal
isodose profiles. Finally, safety and the concomitant regulatory process are discussed.
KEYWORD
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